Well this is what I did to fix my problems.I had this posted in another thread, but its not sticky, I thought I would put it here because I wanted to help.
I was getting permission's problems when I was trying to instill the 4th patch and this is how I fixed that.
(Actually I think this should fix any sort of permissions issues with any game, if you do it with that particular game's contents.)
How to fix Permissions
1. Go into your Applications and find Spore
2. Click on it and choose Show Package contents
3. Click on it and choose Get info (on the "contents" folder)
4. Under Sharing & Permissions, unlock, put in password, and change all privileges to "Read & Write".
5. Click the sprocket/gear thing and click "Apply to enclosed items"
When I did this I was able to get through the patch loader with no problems. (I ended up having more problems but this is how I fixed this one)
Then I couldn't get SPORE to load. I would click the app and it would do its bouncy thing and then just close. The solution I found this problem might end up being a kind of general fix all, but I'm not going to make any guarantees.
General Fix All for SPORE
(Special thanks to NextToGone!!))
1.Move all game data to desktop.
2.Do a COMPLETE uninstall of SPORE. (I used the free AppCleaner app). Just tossing it into your regular trashcan will not do a complete uninstall.
3.Reinstall Spore and all the patches. (You'll need to registration code)
4.Moved back game data into their folders. (I did this by file and not by folder. I just wanted to be sure.)
Be sure that when you do the complete uninstall you don't accidentally delete the game data you moved to your desktop!
The files I moved onto my desktop were the My Spore Creations folder located in My Documents and the Games folder which is...really hidden deep in the Spore. The pathway is users/(whatever your username is)/library/preferences/SPORE preferences/p_drive/user/application data/spore/Games
You can find AppCleaner here http://www.versiontracker.com/dyn/moreinfo/macosx/32740
Once you have AppCleaner installed, put the SPORE app icon into AppCleaner's trash can and follow the direction. ^_^
Be sure to unselect the files that you have moved to your desktop, it will try to delete those.
I hope all this info can help someone else...I kind of just had to just mix and match stuff in different threads until I figured out my own problem.